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Coronavirus

You can get COVID-19 even after vaccination

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Yes, you can get COVID-19 even after vaccination, but there’s a big IF here. That is, IF you do not wait for the stipulated amount of time for the antibodies to develop, IF you do not follow physical distancing norms until the antibodies develop, IF you do not wear masks until the complete 45–60-day vaccination cycle is complete, you can get COVID-19 despite vaccination as well.

This has led to discussions around the Peltzman Effect, a theory popular these days to explain why many people have become infected with the Coronavirus after being vaccinated. Sam Peltzman taught microeconomics at Chicago in 1988. The Peltzman Effect is a theory which states that people are more likely to engage in risky behavior when security measures have been mandated. The Peltzman Effect is named for Sam Peltzman’s postulation about mandating the use of seatbelts in automobiles – that it would lead to more accidents because safety perception increases risk appetite.

Similarly, for COVID-19, there has been a rampant flouting of rules and taking vaccination for granted that the virus is no longer spreading because most people are vaccinated, and this thought is absolutely incorrect. Vaccination does not mean you can blatantly go out and unfollow all rules and regulations that you have been following throughout the pandemic since March 2020. We need to pay attention to some key facts about the vaccine and the Coronavirus here.

  1. Immunity isn’t built in a day: Full-fledged immunity takes a few weeks after the second dose.
  2. Immunity is not 100% shield against the virus: It is more of an added layer of protection for you. The vaccines ensure that even if you do get the viral infection, it will not hit you as hard as it would hit a non-vaccinated individual.
  3. Different vaccines have different efficacies and different mechanisms of actions.  
  4. Research is underway, but as of now, from what we know, not all vaccines are effective against all the variants.  Therefore, until such confirmation, it is safer to assume the vaccine you have taken will not protect you against all the variants of the Coronavirus.
  5. The Ministry of Health & Family Welfare has also said that the protective levels of antibodies generally develop two weeks after receiving the 2nd dose of COVID-19 vaccine.

Putting the Peltzman Effect to action here in the vaccination scenario reflects upon the callous and careless nature of individuals who are roaming around mask-free and not bothered about their risky behavior leading to increased numbers and spread. This means that vaccines are giving a sense of security which leads to increased risky behavior.

But the bigger problem we are facing today is that is that while vaccines neither give immediate protection or full protection (against infection as against death), the sense of security has already started much earlier, even before everyone is vaccinated. For e.g., a lot of people believe if they are around vaccinated people, they are free to leave their masks home. This is completely UNTRUE. While this behavior is dangerous for general public, this can be disastrous for healthcare workers, medical infrastructure and frontline workers who need to be directly available for COVID-19 patients. It is therefore extremely important to keep the Peltzman Effect in mind and be more careful until the effect of vaccination takes us closer to herd immunity.

UIN: 206HP111R

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Coronavirus

Everyone can benefit from a probiotic

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Probiotics are live microorganisms that can be consumed through foods such as curd/yoghurt and through supplemental forms. Studies show that the balance or imbalance of bacteria in your digestive system is linked to overall health and disease and probiotics promote a healthy balance of gut bacteria. They are used in managing and treating a variety of disease states. They are live microorganisms that are known to help improve gut health and include benefits for weight loss, digestive health, immune function and more.

However, current research suggests that probiotic supplements may not benefit everyone and should not be prescribed as a one-size-fits-all supplement. However, when taken in moderation according to your clinician’s advice, probiotics have a plethora of benefits reported in literature. Recent researches point out that changes in the gut microbiota would lead to a systemic inflammation that in different ways would reach the CNS modulating inflammatory pathways and especially the microglia, which could influence responses to treatments. Probiotics have therefore shown antidepressant responses and anti-inflammatory effects.

Studies also show probiotics promote mental flexibility and alleviate stress in healthy older adults, along with causing changes in gut microbiota. The probiotics exert their beneficial effects through modulation of host immune responses, maintain gut homeostasis and produce interferon thereby suppressing the virus induced cytokine storm.

Studies have also shown probiotics could significantly decrease the serum levels of high-sensitivity C-reactive protein and interleukin-6 and increase the serum albumin levels, upper arm circumference, and triceps skinfold thickness in patients undergoing peritoneal dialysis. 

What’s more – Probiotics may potentially have a beneficial role in preventing COVID-19. A recent study quotes, “The efficacy of probiotics has been studied previously on several respiratory tract viral infections. Probiotics comprise living microbes that upon oral administration benefit human health by reshaping the composition of gut microbiota. The close kinship of the gastrointestinal and respiratory tract suggests why the dysfunction of one may incite illness in others. The emerging studies suggest the capability of probiotics to regulate immune responses in the respiratory system.”

However, some studies showed that bacterial overgrowth in the small intestine related to probiotic use can lead to bloating, gas, and other adverse side effects. Additionally, some studies show that probiotic treatment following a course of antibiotics may delay the natural reconstitution of normal gut bacteria.

Therefore, it is recommended that you get a health checkup done starting from consulting your family physician who will advise if you need probiotic supplementation or not.

UIN: 220HP121R

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Fully vaccinated individuals have lower travel risk but can be carriers

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While the debate for vaccinations continues across the globe, there is good news for those who have gotten vaccinated. Vaccination reduces risk of infection about 15-20 days after the dosing is complete. According to the new guidelines issued by the Centre for Disease Control (CDC), US, it is okay to travel domestically if you are fully vaccinated. Which means, you have completed the two doses of the two-dose vaccines or one dose of the J&J vaccine. Or as the CDC puts it’s, “you’re considered fully vaccinated 2 weeks after you receive the last required dose of the COVID-19 vaccine”.

While the US has issued statements that fully vaccinated domestic travelers don’t need to be tested before or after traveling unless their destination requires it, in India the rules for entering different states by air need to be checked well in time because a lot of states mandate a negative RT-PCR test for entry requirements. The Ministry of Health and Family Welfare in India has issued guidelines for International Travel and so has the Ministry of Civil Aviation for domestic travel on 30th March 2021. The DGCA has stated that surveillance across the airports in India will now be increased to ensure all COVID-19 protection protocols are taken into account.

On 13th April 2021, the Indian Railways has also confirmed that in view of the COVID-19 pandemic and related hygiene issues, they have also stopped service of cooked food and replaced the same with Ready to Eat (RTE) meals in trains. In addition, they have ensured that the COVID-19 related protective items such as masks, sanitizers, gloves etc. and takeaway bedroll kits/items, are available for sale through Multi-Purpose Stalls at Stations.

However, as is recommended, even fully vaccinated travelers should still follow the recommendations for traveling safely, including wearing a mask over your nose and mouth, staying 6 feet away from others and avoiding crowds, washing your hands often or using hand sanitizer, self-monitoring for COVID-19 symptoms after traveling, and isolate and get tested if symptoms develop

It is still very important to stay cautious and avoid potential exposures to the coronavirus whenever possible during travel, mainly because vaccination drives are still ongoing, and it is not recommended to travel unguarded since a lot of COVID-19 patients remain asymptomatic and can continue to spread the virus to other unvaccinated people. Also, no vaccine is a 100% fail safe yet, so a very small fraction of fully vaccinated people may still be at risk because emerging variants of the virus add a measure of uncertainty.

UIN: 219HP120R

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Real-world data shows 90% efficacy of Pfizer-BioNTech and Moderna COVID-19 vaccines

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Pfizer-BioNTech and ModernaCOVID-19 vaccines are messenger RNA (mRNA) vaccines but are not available in India yet. These COVID-19 vaccines have been shown to be effective in preventing symptomatic SARS-CoV-2 infection in randomized placebo-controlled Phase III trials.

A new study has shown that the Pfizer-BioNTech and Moderna-NIAID vaccines are effective at preventing infections in the real world. According to the CDC, the authorized mRNA COVID-19 vaccines are effective for preventing SARS-CoV-2 infection in real-world conditions. COVID-19 vaccination is recommended for all eligible persons.

 This study has been published March 29 in Morbidity and Mortality Weekly Report, a publication of the Centers for Disease Control and Prevention (CDC) in the USA. Study analysts have seen that the two-dose vaccine regimen was 90% effective at preventing infections 2 weeks after receiving the second dose.

This new study restores faith in the COVID-19 vaccines and has shown to be highly effective at preventing symptomatic and asymptomatic infections in real-world settings. As per the study results, this data is similar to those from earlier phase 3 clinical trials published in the journal New England Journal of Medicine, which found an efficacy of more than 90% for both the Pfizer-BioNTech and Moderna-NIAID vaccines. This is encouraging news for everyone across the globe because real-world effectiveness is often conservative and therefore, lower due to a number of factors.

Dr. James H. Conway, a pediatric infectious disease specialist at the University of Wisconsin-Madison, said what we really care about is a vaccine’s effectiveness — its real-world potential. He further added that such studies are not only proving how effective the vaccines can be for the studies and research data, but also show the true power of vaccines for real-world COVID-19 pandemic. Therefore, results published in the recent report from the CDC reassure that the vaccines are working as well as they are hoped to, in curbing the pandemic and in turn, stopping the spread of the virus.

Get vaccinated today!!

Read about the vaccination registration procedure here. For details about the type of vaccine and the dosing schedule, read here.

UIN: 210HP115R

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Coronavirus

Sputnik V submitted for DGCI approval for emergency use authorization

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On 13th April 2021, the Drug Controller General of India (DCGI) has approved the Sputnik V COVID-19 vaccine for emergency use.  After Covishield, developed by Oxford University-AstraZeneca and manufactured by the Serum Institute of India (SII), and Bharat Biotech’s Covaxin, this will be the third vaccine against the novel coronavirus that has been granted emergency use authorization in India.

India is the 60th country to approve Sputnik V—the rollout for which is likely to begin by end of April or early May.Currently, the Sputnik V will be imported before the local production kicks in. It is hoped that this emergency approval of Sputnik V will strengthen the government efforts to scale up vaccination, as India is battling the second wave of the pandemic with close to 1.4 lac cases reported on 12th April 2021.

India is also the leading production hub for Sputnik V, since its parent manufacturer company has reached agreements with the leading pharmaceutical companies in India such as Gland Pharma, Hetero Biopharma, Panacea Biotec, Stelis Biopharma, Virchow Biotech aimed at production of more than 850 million doses per year, sufficient to vaccinate more than 425 million people around the world.

The vaccine Sputnik V ranks second among coronavirus vaccines globally in terms of the number of approvals issued by government regulators and has an efficacy of 91.6%. It has shown encouraging results in protection against severe cases of COVID-19 as demonstrated by the data published in one of the leading medical journals The Lancet.

Sputnik V uses two different vectors (adenovirus 26 and adenovirus 5) for the two shots in a course of vaccination, providing immunity with a longer duration than vaccines using the same delivery mechanism for both shots.The safety, efficacy and lack of negative long-term effects of adenoviral vaccines have been proven by more than 250 clinical studies over two decades. There are no strong allergies caused by Sputnik V and with a storage temperature of 2-8 degrees Celsius, the vaccine can be stored in conventional refrigerators without the need to invest in additional cold-chain infrastructure.

UIN: 221HP122R

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37 vaccinated doctors are Covid-19 positive at Delhi’s Sir Gangaram Hospital

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Delhi recorded 7,437 fresh COVID-19 cases on April 8 — the highest single-day surge this year – with 24 more people dying due to the coronavirus infection, taking the death toll to 11,157, according to the Delhi Health Department. In what makes the situation worse, at least 37 doctors of Delhi’s Sir Gangaram Hospital have tested positive for coronavirus, as per the hospital sources on Thursday, 08th April 2021. These doctors had received both doses of COVID-19 vaccination during the first phase of the vaccination drive that was launched on 16th January 2021, thereby cautioning vaccinated individuals to be as cautious as ever to prevent the COVID-19 infection.

The hospital sources have confirmed that a majority of the COVID-19 positive doctors currently have mild symptoms – out of which, 32 doctors are in home isolation and 5 are admitted in the hospital.

Sir Ganga Ram Hospital in New Delhi has been at the forefront of the war against the pandemic that has crippled normal life for more than a year now. Here’s wishing all Corona Warriors a speedy recovery from Health Patrol!

UIN: 217HP119R

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